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Best cold flu reliefs - September 2025

Last Updated - September 11, 2025

1
Best Choice
17% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boiron
17% Off

Oscillococcinum 30 Doses

Picked by 306 people in the last week

Boiron

$27.97

$33.99
(17% Off)

More Details
Main highlights
- THE BOIRON PROMISE: We believe there’s a better way to feel better. Since 1932, we’ve been dedicated to providing the purest medicines made from earth’s best resources
- SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration and the severity of flu-like symptoms when taken at the onset.* Non-drowsy, easy-to-take relief
- HSA & FSA eligible: Oscillococcinum is HSA & FSA eligible
- HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help relieve body aches, headache, fever, chills, and fatigue.* Ideal for ages 2 and up, take at the first sign of flu-like symptoms
- HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum’s meltaway pellets dissolve easily in the mouth; no water, chewing, or swallowing required
- A BETTER WAY TO FEEL BETTER: Homeopathic medicines use highly diluted botanical, biological, or mineral substances to relieve symptoms. They work with your body without the risk of known drug interactions
$27.97
$33.99 (17% Off)
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Vicks

$23.93

More Details
Main highlights
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
- POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. DayQuil and NyQuil relieve bothersome symptoms, such as cough and fever, day or night.
- FEEL BETTER FAST. Just one dose starts working fast to provide effective cold & flu relief
- FAST, POWERFUL MULTI-SYMPTOM RELIEF. Use non-drowsy DayQuil for daytime relief and at night try NyQuil for fast relief so you can rest.
- EFFECTIVE COLD & FLU SYMPTOM RELIEF. DayQuil and NyQuil Cold & Flu medicine temporarily relieve common cold & flu symptoms
$23.93
3
15% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care
15% Off

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Amazon Basic Care

$11.48

$13.54
(15% Off)

More Details
Main highlights
- MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu
- EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
- COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
- COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
- ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
$11.48
$13.54 (15% Off)
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Vicks

$19.97

More Details
Main highlights
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
- RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
- POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
- NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
$19.97
5
Best Value
29% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Nature's Way
29% Off

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

Nature's Way

$13.75

$19.49
(29% Off)

More Details
Main highlights
- Umcka cold + flu care non-drowsy formula with clinically proven Pelargonium sidoides 1X to shorten duration and reduce severity of common cold symptoms and throat, nasal, bronchial irritations, plus Alpha-CF to reduce flu* symptoms
- Nature's Way Cold+Flu Relief provides cold and flu* symptom relief with a multi-action formula for body aches*, congestion, cough, fever*, runny nose*, and sore throat
- Cold + flu* relief made with a proprietary Pelargonium sidoides 1X and Alpha CF.
- Children 6-12 years of age, chew one tablet two times daily. Adults and children 13 years of age and older chew one tablet three times daily
- At Nature’s Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness
$13.75
$19.49 (29% Off)

Best cold flu reliefs - September 2025

Oscillococcinum 30 Doses

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

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Amazon Basic Care Nighttime Cold and Flu Relief Softgels, 6 Hour Cold Medicine, Relieves Major Flu Symptoms So You Can Rest, 48 Count (Pack of 1)

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Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

Nature's Way Cold + Flu Relief FastActives, Umcka, Homeopathic, Fever*, Sore Throat, Cough, Congestion, Phenylephrine Free, Non-Drowsy, Berry Flavored, 10 Packets (Packaging May Vary)

Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

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Nature's Way Cold + Flu Relief Syrup, Umcka, Sore Throat, Cough, Congestion, Fever, Body Aches*, Phenylephrine Free, Homeopathic, Non-Drowsy, Berry Flavored, 4 Fl Oz (Packaging May Vary)